Cialis, or tadalafil, treats erectile dysfunction by inhibiting phosphodiesterase-5 (PDE5). This enzyme normally breaks down cyclic guanosine monophosphate (cGMP), a crucial molecule for achieving and maintaining an erection. By blocking PDE5, Cialis allows cGMP levels to rise, increasing blood flow to the penis.
Understanding cGMP’s Role
CGMP’s presence relaxes the smooth muscles in the penis’ blood vessels, resulting in vasodilation. This increased blood flow fills the erectile tissue, causing an erection. Cialis’s long half-life (17.5 hours) means its effects can last significantly longer than other medications.
Cialis’s Advantages
Compared to other ED medications, Cialis offers a longer duration of action, providing flexibility for sexual activity. However, individual responses vary. Consult your doctor to determine the appropriate dosage and discuss potential side effects.
Dosage and Side Effects
| 5mg daily | Continuous effect | Headache, nasal congestion, back pain |
| 10mg or 20mg as needed | Up to 36 hours | Headache, facial flushing, indigestion |
Important Considerations
Cialis interacts with certain medications, particularly nitrates. Never combine Cialis with nitrates without explicit doctor approval. Additionally, individuals with certain heart conditions should exercise caution and discuss its use with their physician.
Further Information
Always discuss any medication, including Cialis, with your doctor before use. They can assess your individual health needs and determine the most appropriate treatment plan. Self-treating can be dangerous.
