Tadalafil, the active ingredient in generic Cialis, relaxes blood vessels in the penis. This increased blood flow is key to achieving and maintaining an erection.
Specifically, tadalafil inhibits an enzyme called phosphodiesterase-5 (PDE5). PDE5 normally breaks down cyclic guanosine monophosphate (cGMP), a molecule crucial for penile erection. By blocking PDE5, tadalafil allows cGMP levels to remain high, facilitating relaxation of the smooth muscles in the penis.
This process only occurs in the presence of sexual stimulation. Tadalafil doesn’t spontaneously cause erections; it enhances the body’s natural response to sexual arousal.
The 20mg dosage provides a longer duration of action compared to lower doses, often lasting up to 36 hours. This extended window allows for greater flexibility in timing sexual activity.
Remember, individual responses to medication vary. Consult your doctor for personalized advice and to discuss potential side effects.