Interactions with Other Medications: Important Considerations

Always inform your doctor about all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies. Prednisone can interact significantly with several drug classes.

For example, concurrent use with NSAIDs (nonsteroidal anti-inflammatory drugs) like ibuprofen or naproxen increases the risk of stomach ulcers and bleeding. Monitor for gastrointestinal distress.

Combining prednisone with blood thinners, such as warfarin, may heighten the risk of bleeding. Close monitoring of your INR (International Normalized Ratio) is necessary.

Prednisone can also affect blood sugar levels, potentially worsening diabetes. Your doctor might adjust your diabetes medication dosage. Regular blood sugar checks are recommended.

If you’re taking medications for heart conditions, like digoxin, discuss potential interactions with your physician. Prednisone might alter the levels of these medications in your bloodstream.

Individuals using drugs that suppress the immune system should be especially cautious, as prednisone can further weaken your immune response, increasing susceptibility to infections.

Be sure to report any new or worsening symptoms to your healthcare provider immediately. Open communication is key to safe medication use.